Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors from the central nervous procedure, conolidine modulates alternate molecular targets. A Science Advancements review uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabi... https://conolidineforanklepainaft60074.topbloghub.com/44891842/alternative-natural-pain-relief-to-replace-traditional-painkillers-for-dummies