Abstract At the nuclear periphery. associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typically repressive environments in the genome; nonetheless. https://countryscenesaddleryandpetsuppliers.shop/product-category/western-saddles/